Single-gene and single-site tests

There are some instances where single-gene or single syndrome testing may be preferred over a larger genetic testing panel. This is especially true when a patient’s diagnosis or family history is very suggestive for a certain syndrome or there is known familial variant.

Single-site test

Single-site testing is available when there is a known variant in the family. This test is available for any of the 66 genes on our Comprehensive Hereditary Cancer Panel.

Test code Test name Description
93945 Hereditary Cancer Single Site(s) APC, ATM, AXIN2, BAP1, BARD1, BLM, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN1B, CDKN2A (p16, p14), CHEK2, DICER1, EGFR, EPCAM, FANCA, FANCC, FANCM, FH, FLCN, GALNT12, GREM1, HOXB13, MAX, MEN1, MET, MITF, MLH1, MRE11 (MRE11A), MSH2, MSH3, MSH6, MUTYH, NBN, NF1, NTHL1, PALB2, PMS2, POLD1, POLE, POT1, PTCH1, PTEN, RAD50, RAD51C, RAD51D, RECQL, RET, SDHA, SDHAF2, SDHB, SDHC, SDHD, SMAD4, SMARCA4, STK11, SUFU, TMEM127, TP53, TSC1, TSC2, VHL, XRCC2
Single-site test

Single-site testing is available when there is a known variant in the family. This test is available for any of the 66 genes on our Comprehensive Hereditary Cancer Panel.

Hereditary Cancer Single Site(s)

Test code: 93945

APC, ATM, AXIN2, BAP1, BARD1, BLM, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN1B, CDKN2A (p16, p14), CHEK2, DICER1, EGFR, EPCAM, FANCA, FANCC, FANCM, FH, FLCN, GALNT12, GREM1, HOXB13, MAX, MEN1, MET, MITF, MLH1, MRE11 (MRE11A), MSH2, MSH3, MSH6, MUTYH, NBN, NF1, NTHL1, PALB2, PMS2, POLD1, POLE, POT1, PTCH1, PTEN, RAD50, RAD51C, RAD51D, RECQL, RET, SDHA, SDHAF2, SDHB, SDHC, SDHD, SMAD4, SMARCA4, STK11, SUFU, TMEM127, TP53, TSC1, TSC2, VHL, XRCC2

Single-gene test

We have added single-gene tests for specific instances when a patient's personal and/or family history points to a specific gene instead of a broader evaluation.

Test code Test name Description
See description column Single-gene tests* APC – 93797, ATM – 38802, BAP1 – 38803, BLM – 38804, CDH1 – 92568, CDKN2A – 93939, CHEK2 – 93940, EPCAM/MSH2 – 91471, FH – 38805, FLCN – 38806, HOXB13 – 38807, MEN1 – 93942, MITF – 38808, MLH1 – 91460, MSH6 – 91458, MUTYH – 93944, NF1 – 93941, PALB2 – 92571, PMS2 – 91457, PTEN – 92566, RET – 93796, SMARCA4 – 38809, STK11 – 92565, TP53 – 92560, VHL – 93943

* All panel components are available individually

Single-gene test

We have added single-gene tests for specific instances when a patient's personal and/or family history points to a specific gene instead of a broader evaluation.

Single-gene tests*

APC – 93797, ATM – 38802, BAP1 – 38803, BLM – 38804, CDH1 – 92568, CDKN2A – 93939, CHEK2 – 93940, EPCAM/MSH2 – 91471, FH – 38805, FLCN – 38806, HOXB13 – 38807, MEN1 – 93942, MITF – 38808, MLH1 – 91460, MSH6 – 91458, MUTYH – 93944, NF1 – 93941, PALB2 – 92571, PMS2 – 91457, PTEN – 92566, RET – 93796, SMARCA4 – 38809, STK11 – 92565, TP53 – 92560, VHL – 93943

* All panel components are available individually

Simplified ordering process

Easily find detailed information for each test in the Quest Diagnostics test directory and order your Hereditary Cancer test collection kits by completing this online form. To complete the online order form, you’ll need your Quest Diagnostics Account Number.

If you aren’t sure if you have an account, call us at 1.866.MY.QUEST (1.866.697.8378) and we’ll be happy to look it up. We can quickly create an account for you today, so you’ll have everything you need to ensure seamless service—from kit delivery, to speedy order processing, to result delivery—including requisition forms, customer service contact information, and scheduled pick-up service when you need it.

Once your account is set up, ask the Client Services Representative to send your Quest Advanced Hereditary Cancer starter kits to you or complete the online form.

As always, for clinical consultation on test selection and results interpretation, you can call 1.866.GENE.INFO (1.866.436.3463).

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