Comprehensive Hereditary Cancer Panel (66 genes)

Test code: 38600

Multi-cancer, 66-gene panel tests for variants in these genes: APC, ATM, AXIN2, BAP1, BARD1, BLM, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN1B, CDKN2A, CHEK2, DICER1, EGFR, EPCAM, GREM1, FANCA, FANCC, FANCM, FH, FLCN, GALNT12, HOXB13, MAX, MEN1, MET, MITF, MLH1, MRE11 (MRE11A), MSH2, MSH3, MSH6, MUTYH, NBN, NF1, NTHL1, PALB2, PMS2, POLD1, POLE, POT1, PTCH1, PTEN, RAD50, RAD51C, RAD51D, RECQL, RET, SDHA, SDHAF2, SDHB, SDHC, SDHD, SMAD4, SMARCA4, STK11, SUFU, TMEM127, TP53, TSC1, TSC2, VHL, XRCC2

GSP or CPT coding^*:
For breast: 81432, 81433
For colon: 81435, 81436

Guideline-Based Hereditary Cancer Panel (32 genes)

Test code: 38611

Multi-cancer, 32-gene panel tests for variants in these genes: APC, ATM, AXIN2, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN2A (p16,p14), CHEK2, EPCAM, GREM1, HOXB13, MLH1, MSH2, MSH3, MSH6, MUTYH, NBN, NF1, NTHL1, PALB2, POLD1, POLE, PMS2, PTEN, RAD51C, RAD51D, SMAD4, STK11, TP53

GSP or CPT coding^*:
For breast: 81432, 81433
For colon: 81435, 81436

Hereditary Breast Cancer Panel (16 genes)

Test code: 38621

Tests for variants in 16 genes predominantly associated with cancers of the breast, prostate, and other tissues and including these genes: ATM, BRCA1, BRCA2, CDH1, CHEK2, EPCAM, MLH1, MSH2, MSH6, NBN, NF1, PALB2, PMS2, PTEN, STK11, TP53

GSP or CPT coding^*: 81432, 81433

Hereditary Colorectal Cancer Panel (19 genes)

Test code: 38631

Tests for variants in 19 genes associated with increased risk for colorectal cancer including: APC, AXIN2, BMPR1A, CDH1, EPCAM, GREM1, MLH1, MSH2, MSH3, MSH6, MUTYH, NTHL1, PMS2, POLD1, POLE, PTEN, SMAD4, STK11, TP53

GSP or CPT coding^*: 81435, 81436

Hereditary Endocrine Cancer Panel (12 genes)

Test code: 38641

Tests for variants in 12 genes associated with increased risk for paragangliomas, pheochromocytomas, and endocrine cancer: FH, MAX, MEN1, NF1, RET, SDHA, SDHAF2, SDHB, SDHC, SDHD, TMEM127, VHL

GSP or CPT coding^*: 81437, 81438

BRCA Panel Plus (7 genes)

Test code: 92587

Detects variants in BRCA1, BRCA2, CDH1, PALB2, PTEN, STK11, TP53

GSP or CPT coding^*: 81162, 81307, 81321, 81323, 81351, 81404, 81405, 81406, 81479

BRCA Panel (BRCA1, BRCA2)

Test code: 91863

Detects variants in the BRCA1 and BRCA2 genes which are the most common causes of hereditary breast and ovarian cancers

GSP or CPT coding^*: 81162

BRCA Ashkenazi Jewish Screen

Test code: 91864

Detects 3 variants within BRCA1 and BRCA2 that are commonly found in the Ashkenazi Jewish population

GSP or CPT coding^*: 81212

BRCA Ashkenazi Jewish Screen w/Reflex to BRCA Panel (BRCA1, BRCA2)

Test code: 92140

Ashkenazi Jewish screen; if negative reflex to BRCA Panel (BRCA1 and BRCA2)

GSP or CPT coding^*: 81212 with possible reflex to 81162 at an additional charge

BRCA1 and BRCA2 Deletion and Duplication

Test code: 91866

Detects large deletion/duplication variants in the BRCA1 and BRCA2 genes not detectable by DNA sequencing

GSP or CPT coding^*: 81164

Lynch Syndrome Panel (5 genes)

Test code: 91461

Detects pathogenic variants in the MLH1, MSH2, MSH6, PMS2, and EPCAM (del/dup only) genes

GSP or CPT coding^*: 81295, 81297, 81292, 81294, 81298, 81300, 81317, 81319, 81403

Nevoid Basal Cell Carcinoma (NBCCS) (Gorlin) Syndrome Panel (PTCH1, SUFU)

Test code: 38651

Detects variants in PTCH1 and SUFU

GSP or CPT coding^*: 81479

Tuberous Sclerosis Complex Panel (TSC1, TSC2)

Test code: 38661

Detects variants in TSC1 and TSC2

GSP or CPT coding^*: 81405, 81406 (x2), 81407

Juvenile Polyposis Panel (BMPR1A, SMAD4)

Test code: 94053

Detects pathogenic and VUS variants in the BMPR1A and SMAD4 genes

GSP or CPT coding^*: 81405, 81406, 81479

Hereditary Cancer Single Site(s)

Test code: 93945

APC, ATM, AXIN2, BAP1, BARD1, BLM, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN1B, CDKN2A (p16, p14), CHEK2, DICER1, EGFR, EPCAM, FANCA, FANCC, FANCM, FH, FLCN, GALNT12, GREM1, HOXB13, MAX, MEN1, MET, MITF, MLH1, MRE11 (MRE11A), MSH2, MSH3, MSH6, MUTYH, NBN, NF1, NTHL1, PALB2, PMS2, POLD1, POLE, POT1, PTCH1, PTEN, RAD50, RAD51C, RAD51D, RECQL, RET, SDHA, SDHAF2, SDHB, SDHC, SDHD, SMAD4, SMARCA4, STK11, SUFU, TMEM127, TP53, TSC1, TSC2, VHL, XRCC2

GSP or CPT coding^*: Please call Genomic Client Services 1.866.GENE.INFO (1.866.436.3463) for more information

Single-gene tests

APC – 93797, ATM – 38802, BAP1 – 38803, BLM – 38804, CDH1 – 92568, CDKN2A – 93939, CHEK2 – 93940, EPCAM/MSH2 – 91471, FH – 38805, FLCN – 38806, HOXB13 – 38807, MEN1 – 93942, MITF – 38808, MLH1 – 91460, MSH6 – 91458, MUTYH – 93944, NF1 – 93941, PALB2 – 92571, PMS2 – 91457, PTEN – 92566, RET – 93796, SMARCA4 – 38809, STK11 – 92565, TP53 – 92560, VHL – 93943

GSP or CPT coding^*: Please call Genomic Client Services 1.866.GENE.INFO (1.866.436.3463) for more information

*The CPT codes provided are based on American Medical Association guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.