Comprehensive Hereditary Cancer Panel
The Comprehensive Hereditary Cancer Panel includes 66 genes associated with a broad spectrum of hereditary cancers. This can include, but is not limited to, cancers of the breast, colon, endometrium, ovary, pancreas, prostate, rectum, neuroendocrine system, and other tissues. This panel would be used if the clinician desires comprehensive analysis of genes related to a variety of cancers containing clinically actionable genes as well as emerging genes.
| Test code | Test name | Description | GSP or CPT coding* |
|---|---|---|---|
| 38600 | Comprehensive Hereditary Cancer Panel
(66 genes) |
Multi-cancer, 66-gene panel tests for variants in these genes: APC, ATM, AXIN2, BAP1, BARD1, BLM, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN1B, CDKN2A, CHEK2, DICER1, EGFR, EPCAM, GREM1, FANCA, FANCC, FANCM, FH, FLCN, GALNT12, HOXB13, MAX, MEN1, MET, MITF, MLH1, MRE11 (MRE11A), MSH2, MSH3, MSH6, MUTYH, NBN, NF1, NTHL1, PALB2, PMS2, POLD1, POLE, POT1, PTCH1, PTEN, RAD50, RAD51C, RAD51D, RECQL, RET, SDHA, SDHAF2, SDHB, SDHC, SDHD, SMAD4, SMARCA4, STK11, SUFU, TMEM127, TP53, TSC1, TSC2, VHL, XRCC2 | For breast: 81432, 81433 For colon: 81435, 81436 |
*The CPT codes provided are based on American Medical Association guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
Guideline-Based Hereditary Cancer Panel
The Guideline-Based Hereditary Cancer Panel includes clinically actionable analysis of 32 genes associated with a broad spectrum of hereditary cancers. This can include, but is not limited to, cancers of the breast, colon, endometrium, ovary, pancreas, prostate, rectum, skin, and other tissues. This panel would be used if the clinician desires comprehensive analysis of genes related to more common cancers.
| Test code | Test name | Description | GSP or CPT coding* |
|---|---|---|---|
| 38611 | Guideline-Based Hereditary Cancer Panel
(32 genes) |
Multi-cancer, 32-gene panel tests for variants in these genes: APC, ATM, AXIN2, BARD1, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN2A (p16,p14), CHEK2, EPCAM, GREM1, HOXB13, MLH1, MSH2, MSH3, MSH6, MUTYH, NF1, NTHL1, PALB2, POLD1, POLE, PMS2, PTEN, RAD51C, RAD51D, SMAD4, STK11, TP53 | For breast: 81432, 81433 For colon: 81435, 81436 |
*The CPT codes provided are based on American Medical Association guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
Comprehensive Hereditary Cancer Panel (66 genes)
Test code: 38600
Multi-cancer, 66-gene panel tests
for variants
in these genes: APC, ATM, AXIN2, BAP1, BARD1, BLM,
BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN1B, CDKN2A, CHEK2, DICER1, EGFR, EPCAM, GREM1, FANCA,
FANCC, FANCM, FH, FLCN, GALNT12, HOXB13, MAX, MEN1, MET, MITF, MLH1, MRE11 (MRE11A), MSH2, MSH3, MSH6,
MUTYH, NBN, NF1, NTHL1, PALB2, PMS2, POLD1, POLE, POT1, PTCH1, PTEN, RAD50, RAD51C, RAD51D, RECQL,
RET, SDHA, SDHAF2, SDHB, SDHC, SDHD, SMAD4, SMARCA4, STK11, SUFU, TMEM127, TP53, TSC1, TSC2, VHL,
XRCC2
GSP or CPT coding*:
For breast: 81432, 81433
For colon: 81435, 81436
Guideline-Based Hereditary Cancer Panel
Test code: 38611
Multi-cancer, 32-gene panel tests
for variants in these genes: APC, ATM, AXIN2, BMPR1A, BRCA1, BRCA2,
BRIP1, CDH1, CDK4, CDKN2A (p16,p14), CHEK2, EPCAM, GREM1, HOXB13, MLH1, MSH2, MSH3, MSH6, MUTYH, NBN,
NF1, NTHL1, PALB2, POLD1, POLE, PMS2, PTEN, RAD51C, RAD51D, SMAD4, STK11, TP53
GSP or CPT coding*:
For breast: 81432, 81433
For colon: 81435, 81436
Simplified ordering process
Easily find detailed information for each test in the Quest Diagnostics test directory and order your Hereditary Cancer test collection kits by completing this online form. To complete the online order form, you’ll need your Quest Diagnostics Account Number.
If you aren’t sure if you have an account, call us at 1.866.MY.QUEST (1.866.697.8378) and we’ll be happy to look it up. We can quickly create an account for you today, so you’ll have everything you need to ensure seamless service—from kit delivery to speedy order processing and results delivery—including requisition forms, customer service contact information, and scheduled pick-up service when you need it.
Once your account is set up, ask the Client Services Representative to send your Quest Advanced Hereditary Cancer starter kits to you or complete the online form.
As always, for clinical consultation on test selection and results interpretation, you can call 1.866.GENE.INFO (1.866.436.3463).